Research Projects (Ongoing)
Duration: 2023-2026
Project Coordinator of project entitled ‘Process optimization and scale-up of extremozymes from microbiome of Himalayan hot springs and cold deserts for industrial application’. Sponsored by Department of Biotechnology (DBT).
Research Projects (Completed)
International :
Project investigator of Indo-Swiss Collaboration in Biotechnology (ISCB):
Duration: 2004-2007
“Bioremediation of HCH and PNP Contaminated soil by Bioaugmentation: Proof of Concept at Pilot Scale”. Sponsored by the ISCB, Swiss Federal Institute of Technology, Switzerland (Mar 2004 - Aug 2007).
Project Investigator of Indo-Australian Collaboration in Biotechnology (IACB) project entitled
Duration: 2007-2010
Project Investigator of Indo-Australian Collaboration in Biotechnology (IACB) project entitled, “Enabling Technologies for the Enzymatic Bioremediation of Cyclic Organochlorine Residues”. Sponsored by Department of Biotechnology, Govt. of India (Jul 2007 - Jul 2010).
Project Investigator of Indo-Swiss Collaboration in Biotechnology (ISCB) Phase III:
Duration: 2008-2010
Project Investigator of Indo-Swiss Collaboration in Biotechnology (ISCB) Phase III: “Environmental Risk and Bioremediation of Hexachlorocyclohexane Isomers”. Sponsored by the ISCB, Swiss Federal Institute of Technology, Switzerland (Sep 2008 - Sep 2010).
Project Leader in DST-DAAD Programme :
Duration: 2001-2004
Project Leader in DST-DAAD Programme: “Genomic Mapping of the Chromosome and Development of a System for the Generation of Rifamycin Analogs in Amycolatopsis mediterranei”. Sponsored by Department of Science and Technology, Govt. of India (May 2001 - May 2004).
Project investigator :
“Mining linA and linB variants for the development of enzymatic bioremediation of Hexachlorocyclohexane”
Duration: 2012-2014
Project investigator of “Mining linA and linB variants for the development of enzymatic bioremediation of Hexachlorocyclohexane”. Sponsored by Department of Science & Technology (Jul 2012 - Sep 2014).
Project Investigator of personnel exchange programme entitled
Duration: 2013-2015
Project Investigator of personnel exchange programme entitled “Assessing Natural and Stimulated Biodegradation of the Pesticide Hexachlorocyclohexane (HCH) at Contaminated Field Sites Using Compound-Specific Stable Isotope Analysis (CSIA)”. Sponsored by Department of Science & Technology-Deustscher Akademischer Austausch Di (German Academic Exchange Service) (DST-DAAD) (Apr 2013 – Apr 2015).
Collaborator in Project entitled
Duration: 2014-2016
Collaborator in Project entitled “Tracking biotransformation of Hexachlorocyclohexane isomers by Compound-Specific isotopy Analysis” with Dr. Hans-Peter Kohler and Dr. Thomas Hofstelter. Sponsored by Swiss National Science Foundation.
National :
Co-investigator of project :
“Accumulation, metabolism and effects of organo-chlorine insecticides on microorganisms”.
Duration: 1981-1984
Co-investigator of project: “Accumulation, metabolism and effects of organo-chlorine insecticides on microorganisms”. Sponsored by Ministry of Forests and Wild Life, Govt. of India. (Jan 1981- Jun 1984).
Principal Investigator of a project :
Duration: 1983-1986
Principal Investigator of a project: “Accumulation, metabolism and effects of organophosphorus insecticides on microorganisms”. Spon¬sored by the Ministry of Wild Life and Forests, Government of India (Jun 1983 - Nov 1986).
Principal Investigator of a project :
“Effects of pesticides on Rhizobium-legume symbiosis”
Duration: 1987-1990
Principal Investigator of a project: “Effects of pesticides on Rhizobium-legume symbiosis”. Spon¬sored by the Ministry of Wild Life and Forests, Government of India (Jan 1987 - May 1990).
Co-investigator of a project :
“Survey of pesticide residues from food commodities in Delhi and surrounding areas”
Duration: 1987-1990
Co-investigator of a project: “Survey of pesticide residues from food commodities in Delhi and surrounding areas”. Spon¬sored by Ministry of Health, Government of India and WHO (Jan 1987 - Dec 1990).
Co-ordinator of project :
“College Science Improvement programme (COSIP)”
Duration: 1987-1990
Co-ordinator of project: “College Science Improvement programme (COSIP)”. Sponsored by University Grants Commission, New Delhi (Jul 1987 - Jun 1990).
Principal Investigator of the Project :
“Indigenization and Genetic Manipulations of Rifamycin Production in Amycola¬topsis mediterranei (Nocardia mediterranei)”.
Duration: 1992-1997
Principal Investigator of the Project: “Indigenization and Genetic Manipulations of Rifamycin Production in Amycola¬topsis mediterranei (Nocardia mediterranei)”. Sponsored by Department of Biotechnolo¬gy, Govt. of India (Dec 1992 - Nov 1997).
Principal Investigator of the Project :
“Manipulation of Catabolic Genes for Detoxification of Xenobiotics”
Duration: 1993-1996
Principal Investigator of the Project, “Manipulation of Catabolic Genes for Detoxification of Xenobiotics”. Sponsored by the Ministry of Environment and Forests, Govt. of India from (Apr 1993 - Sep 1996).
Principal Investigator of the Project :
“Cloning and Characterization of rifamycin biosynthetic genes and development of a system for the generation of hybrid antibiotics”.
Duration: 1997-2000
Principal Investigator of the Project, “Cloning and Characterization of rifamycin biosynthetic genes and development of a system for the generation of hybrid antibiotics”. Sponsored by Department of Bio¬technology, Govt. of India (Apr 1997 – Jun 2000).
Principal Investigator of the Project :
“Cloning and characterization of catabolic genes of gamma-HCH and its isomers in Sphingomonas paucimobilis”
Duration: 1997-2000
Principal Investigator of the Project: “Cloning and characterization of catabolic genes of gamma-HCH and its isomers in Sphingomonas paucimobilis”. Sponsored by the Department of Biotechnology, Govt. of India (Apr 1997 - Mar 2000).
Principal Investigator of the Project :
“Microbial Biodiversity of Indigenous Actinomycetes Germplasm”
Duration: 1999–2003
Principal Investigator of the Project: “Microbial Biodiversity of Indigenous Actinomycetes Germplasm”. Sponsored by the Department of Biotechnology, Govt. of India (Jul 1999 - Jul 2003).
Co–Investigator of the Project :
“Cloning and Characterization of Ligninase/laccase genes from White Rot- Fungus”.
Duration: 1999-2003
Co–Investigator of the Project: “Cloning and Characterization of Ligninase/laccase genes from White Rot- Fungus”. Sponsored by Department of Biotechnology, Govt. of India from (Apr 1999 - Mar 2003).
Principal Investigator of the Project :
“Genetic Engineering of Rifamycin gene Cluster in Amycolatopsis mediterranei for the production of Rifamycin Analogs”.
Duration: 2001-2004
Principal Investigator of the Project: “Genetic Engineering of Rifamycin gene Cluster in Amycolatopsis mediterranei for the production of Rifamycin Analogs”. Sponsored by Department of Biotechnology, Govt. of India (Apr 2001 - Mar 2004).
Project Investigator of the project :
“Development of suitable probes for tracking the organisms released for biodegradation of soil contaminated with chlorinated and nitro pesticides”.
Duration: 2001-2005
Project Investigator of the project “Development of suitable probes for tracking the organisms released for biodegradation of soil contaminated with chlorinated and nitro pesticides”. Sponsored by Department of Biotechnology, Govt. of India from (Aug 2001 - Mar 2005).
Project Investigator of the project :
“Characterization and molecular analysis of some PAHs (Phenenthrene, Pyrene and Benzo (a) pyrene) degrading pathways by bacteria through metabolic Engineering”.
Duration: 2003-2004
Project Investigator of the project “Characterization and molecular analysis of some PAHs (Phenenthrene, Pyrene and Benzo (a) pyrene) degrading pathways by bacteria through metabolic Engineering”. Sponsored by Department of Biotechnology, Govt. of India (Apr 2003 - Mar 2006).
Project Investigator of the project :
“Decontamination and Microbial diversity of HCH, p-Nitrophenol and Chloropyrifos contaminated soils from dumping sites”.
Duration: 2004-2007
: Project Investigator of the project “Decontamination and Microbial diversity of HCH, p-Nitrophenol and Chloropyrifos contaminated soils from dumping sites”. Sponsored by Department of Biotechnology, Govt. of India (Apr 2004 - Mar 2007).
Project Investigator :
“Improvement and Development of Cloning Vector transformation system for species of Amycolatopsis”.
Duration: 2005-2008
Project Investigator of “Improvement and Development of Cloning Vector transformation system for species of Amycolatopsis”. Sponsored by Department of Science and Technology, Govt. of India (Jan 2005 - Jan 2008).
Project Investigator :
“Genome Sequencing of Rifamycin Producing Actinomycete Amycolatopsis mediterranei S699”
Duration: 2004-2008
Project Investigator of “Genome Sequencing of Rifamycin Producing Actinomycete Amycolatopsis mediterranei S699”. Sponsored by Department of Biotechnology, Govt. of India (Apr 2004 - Mar 2008).
Project Investigator of the Indo-Swiss Joint Research Project (ISJRP)
Duration: 2005-2008
Project Investigator of the Indo-Swiss Joint Research Project (ISJRP), “Isolation, Characterization and Mutagenesis of Long-range acting bacterial transcription regulators with receptor domains in aromatic compounds (acronym: TRAROMAT)”. Sponsored by Department of Science and Technology, Govt. of India (Dec 2005 - Dec 2008).
Project investigator :
“Screening for Bio-molecules from Microbial Diversity Collected from Different Ecological Niches”
Duration: 2007-2011
Project investigator of “Screening for Bio-molecules from Microbial Diversity Collected from Different Ecological Niches”. Sponsored by Department of Biotechnology, Govt. of India (Oct 2007 - Mar 2011).
Project investigator :
“Construction of Bacterial Biosensors for Detection of Aromatic Hydrocarbons”
Duration: 2008-2012
Project investigator of “Construction of Bacterial Biosensors for Detection of Aromatic Hydrocarbons”. Sponsored by Department of Biotechnology, Govt. of India (Apr 2008 - Mar 2011).
Co-Project investigator :
“Molecular Analysis of Agrocin Producing Agrobacterium radiobactor for Biological Control of Crown Gall in Stone Fruits”.
Duration: 2008-2012
Co-Project investigator of “Molecular Analysis of Agrocin Producing Agrobacterium radiobactor for Biological Control of Crown Gall in Stone Fruits”. Sponsored by Indian Council of Agricultural Research (ICAR) (Apr 2008 - Mar 2012).
Project investigator :
“Understanding Individual & Community Genomes of Bacteria using New Generation Sequencing Technologies”.
Duration: 2009-2012
Project investigator of “Understanding Individual & Community Genomes of Bacteria using New Generation Sequencing Technologies”. Sponsored by University of Delhi under DU/ DST – PURSE Grant (Dec 2009 - Sep 2013).
Project Investigator :
“Genotyping and Isolation of Sphingomonads from HCH contaminated Agricultural soils and their application in Bioremediation”.
Duration: 2007-2014:
Project Investigator of “Genotyping and Isolation of Sphingomonads from HCH contaminated Agricultural soils and their application in Bioremediation”. Sponsored by National Bureau of Agriculturally Important Microorganisms (NBAIM) (ICAR) (April 2007 - March 2014).
Project investigator :
“Understanding Genome Organisation and Gene Expression in Response to Different Hexachlorocyclohexane (HCH) Isomers in HCH Degrading Bacteria and the HCH Dumpsite”.
Duration: 2012-2015
Project investigator of “Understanding Genome Organisation and Gene Expression in Response to Different Hexachlorocyclohexane (HCH) Isomers in HCH Degrading Bacteria and the HCH Dumpsite”. Sponsored by Department of Biotechnology (DBT) (Apr 2012 - Mar 2015).
Project investigator :
“Isolating the Natural Existing Hexachlorocyclohexane Dehydrochlorinase (LinA) & Haloalkane Dehalogenase (LinB)”.
Duration: 2012-2015
Project investigator of “Isolating the Natural Existing Hexachlorocyclohexane Dehydrochlorinase (LinA) & Haloalkane Dehalogenase (LinB) Variants from Hexachlorocyclohexane Contaminated Dumpsite by using Metagenomic Approach”. Sponsored by Department of Science & Technology (Jun 2012 - May 2015).
Project investigator :
Sponsored by National Bureau of Agriculturaly Important Microorganisms (NBAIM) (ICAR)
Duration: 2014-2017
Project investigator of “Microbial metagenomic analysis of hotspring situated atop the Himalyan ranges at Manikaran, Himachal Pradesh, India”. Sponsored by National Bureau of Agriculturaly Important Microorganisms (NBAIM) (ICAR) (April 2014 to March 2017) Funds: 48.637 Lacs.
Project investigator :
“All India Network Project on Soil-Biodiversity Biofertilizers (XIth Plan)”
Duration: 2007-2018
Project investigator of “All India Network Project on Soil-Biodiversity Biofertilizers (XIth Plan)”. Sponsored by Indian Council of Agricultural Research (ICAR) (April 2007 to March 2018) Funds: 22 Lacs.
Project Investigator :
Production of rifamycin analogues against multi-drug resistant (MDR)
Duration: 2015-2018
Project Investigator of “Production of rifamycin analogues against multi-drug resistant (MDR) strains of Mycobacterium tuberculosis by the manipulation of rifamycin polyketide biosynthetic gene cluster of Amycolatopsis mediterranei S699 and understanding the changes in human microbiome under antibiotic treatment regimen in patients suffering from tuberculosis”. Sponsored by Department of Biotechnology (DBT) from October 2015 to September 2018. Funds: 64 Lacs.
Project Co-investigator :
“Characterization of Free Living Ciliated Protists as indicators of pollution and their impact on the micro-ecology of Yamuna River flowing through National Capital Region (NCR) of Delhi, India”.
Duration: 2016-2019
Project Co-investigator of “Characterization of Free Living Ciliated Protists as indicators of pollution and their impact on the micro-ecology of Yamuna River flowing through National Capital Region (NCR) of Delhi, India”. Sponsored by Department of Science & Technology (DST). Funds- 55.76 Lacs.
Project Investigator :
“To study the microbial diversity associated with fish gut by using culture dependent and independent approaches”.
Duration: 2016-2018
Project Investigator of “To study the microbial diversity associated with fish gut by using culture dependent and independent approaches”. Sponsored by AMAAS and National Bureau of Agriculturally Important Microorganisms (NBAIM). Funds: ₹ 19.5 Lacs.
Project Coordinator and Investigator :
“Exploring diversity, functional dynamics and biotechnological applications of bacterial communities inhabiting hot water spring atop the Himalayan ranges at Manikaran, Himachal Pradesh, India”.
Duration: 2017-2020
Project Coordinator and Investigator of “Exploring diversity, functional dynamics and biotechnological applications of bacterial communities inhabiting hot water spring atop the Himalayan ranges at Manikaran, Himachal Pradesh, India”. Sponsored by Department of Biotechnology (DBT). Funds: 52.2 Lacs.
Project Coordinator and Investigator :
“Remediation and reclamation of HCH dumpsite by using microbial bioremediation technology”
Duration: 2018-2021
Project Coordinator and Investigator of “Remediation and reclamation of HCH dumpsite by using microbial bioremediation technology”. Sponsored by Department of Biotechnology (DBT) from April 2018 to September 2021. Funds: ₹113 Lacs.
Project Advisor :
"Up-scaling and commercialization of 24-desmethyl rifampicin effective against major first line drug rifampicin resistant strains of Mycobacterium tuberculosis"
Duration: 2020-2022
Project Advisor of "Up-scaling and commercialization of 24-desmethyl rifampicin effective against major first line drug rifampicin resistant strains of Mycobacterium tuberculosis". Sponsored by Biotechnology Industry Research Assistance Council (BIRAC) from February, 2020 to February, 2022. Budget: 49 lacs
Project Investigator :
“GIS-based mapping of microbial diversity across the Ganges for ecosystem services”.
Duration: 2019-2022
Project Investigator of “GIS-based mapping of microbial diversity across the Ganges for ecosystem services”. Sponsored by National Mission for Clean Ganga from August, 2019 to August 2022. Budget: 47.25 lacs
